Variants of the industrially relevant protease KP-43 with suppressed activity under alkaline conditions developed using expanded genetic codes

In the present study, we attempted to control the pH profile of the catalytic activity of the industrially relevant alkaline protease john tory hair KP-43, by incorporating 3-nitro-l-tyrosine and 3-chloro-l-tyrosine at and near the catalytic site.Thirty KP-43 variants containing these non-natural amino acids at the specific positions were synthesiz

read more

Hereditary separability in Hausdorff continua

We consider those Hausdorff continua S such that each separable subspace of S is hereditarily separable.Due to results of Ostaszewski and Rudin, respectively, all monotonically normal spaces trucf and therefore all continuous Hausdorff images of ordered compacta also have this property.Our study focuses on the structure cath kidston forget me not o

read more

Considerations as to secondary education, school dropout and youth in the context of the pandemic in Argentina

Abstract Historically, the Latin American region presents evident social and educational inequalities that are represented in the educational trajectories of its youth dodge dart radiator hose populations; conditions that seem to be exacerbated in a pandemic.The objective of this text is to analyze the situation of secondary education in Latin Amer

read more


Most frequent gait patterns in diplegic spastic cerebral palsy

OBJECTIVE: To identify gait patterns in a large group of children with diplegic cerebral palsy and to characterize each group according to age, Gross Motor Function Classification System (GMFCS) level, Gait Deviation Index (GDI) and previous surgical procedures.METHODS: One thousand eight hundred and five patients were divided in seven groups regar

read more